I"m starting Butterbur extract tonight, 75 mg twice a day. My neurologist thinks it might help with the migraine prevention. In addition to the B2 400mg, Propranolol, Nortriptyline, and Topamax. I'm also taking Magnesium. I'm on week 2 of the Prednisone which seems to be helping with the rebound headaches. I haven't taken any pain meds in two weeks :) WOO Hoo! And I only have 4 days of school left.